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Yoshida et al followed 168 patients with proteinuria with type 2 diabetes for 10 years and found in an analysis of the clinical course of the three genotypes of ACE that the majority of patients with the DD genotype (95%) evolved to ESRD within 10 years36. Further reference DD mlb jersey forum xcitefun genotype to increase mortality when dialysis is initiated. Two recent studies have confirmed that the D allele has a mlb jersey forum xcitefun deleterious effect on renal function in patients with type 2 diabetes37,38.
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